By January 15, 2027, will the study on the PanChol oral cholera vaccine booster trial (NCT05657782), first posted as a preprint on medRxiv, be published in a peer-reviewed journal?

A phase 1a booster study for PanChol, a single-dose oral cholera vaccine, suggests a single dose may be sufficient for durable immunity. Publication in a peer-reviewed journal would be a key step towards further clinical development, as existing vaccines require multiple doses and have lower efficacy in children.

How this question entered the record and how it will be resolved.

Resolution criteria

This question resolves to Yes if the study, registered as NCT05657782, appears in a peer-reviewed journal by the resolution date. The question resolves to No otherwise. Resolution will be determined by searching for the study on PubMed, Google Scholar, and the original medRxiv preprint page, which typically links to the published version.

Expected resolution

Jan 15, 2027

• Booster trial suggests single-dose PanChol cholera vaccine is sufficient